The Effects of Sodium Cyclamate on the Growth of Chlamydomonas reinhardi (Wild Type)

The growth of Chlamydomonas reinhardi (wild type—) was curbed corresponding to the increased amount of sodium cyclamate in the culture medium. Some inhibition of growth occurred at 0.00001% (0.1 ppm) cyclamate with increased inhibition at higher concentrations of cyclamate. Concentrations of 0.1% (1000 ppm) sodium cyclamate and above were excluded because of the osmotic effects that these concentrations imposed. The effect of cyclamate on the growth curve of reinhardi was a delayed rather than an immediate one. As cells in the logarithmic phase of growth were used as inocula for growth curves, the primary effect of cyclamate was neither the onset of a lag phase nor a decrease in logarithmic growth rate, but a decrease in total cell crop. In an effort to explain this type of growth inhibition, assays were done on both the chlorophyll content and cyclohexylamine content of cultures. (Cyclohexylamine is a known, injurious metabolite of cyclamate.)

Title	The Effects of Sodium Cyclamate on the Growth of Chlamydomonas reinhardi (Wild Type)
Creator	Figley, W. K.
	Majumdar, Shyamal K.
	Mineo, Lorraine
Publisher	Proceedings of the Pennsylvania Academy of Science
Academic Department	Biology
Division	Natural Sciences
Organization	Lafayette College
Date Issued	1975
Date Available	2023-06-26
Type	Article
Language	English
Bibliographic Citation	Mineo, L., W. K. Figley, S. K. Majumdar (1975) "The Effects of Sodium Cyclamate on the Growth of Chlamydomonas reinhardi (Wild Type)." Proceedings of the Pennsylvania Academy of Science 49 (2): 103-106.
Standard Identifier	Handle 10385/qj72p860c
Permalink	http://hdl.handle.net/10385/qj72p860c
Rights Statement	In Copyright
Rights Holders	Penn State University Press