Teratologic Evaluation of Hexachlorophene in Mice
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Abstract
- Hexachlorophene was administered subcutaneously to pregnant STS mice on days 3-8,7-12, or 11-16 of gestation at levels of 0 (DMSO control), 12.5 and 25 mg/kg/day. The females were sacrificed on the 19th day and the fetuses were examined for viability and external abnormalities. Implantations and resorbtions were recorded. All the concentrations of the chemical were found to increase fetal resorbtion and mortality. Examinations of fetuses from the control groups and the experimental groups failed to reveal any teratogenic effects of hexachlorophene.
| Title | Teratologic Evaluation of Hexachlorophene in Mice |
|---|---|
| Creator | Filippone, E. J. |
| Majumdar, Shyamal K. | |
| Sobel, H. J. | |
| Franco, R. A. | |
| Publisher | Proceedings of the Pennsylvania Academy of Science |
| Academic Department | Biology |
| Division | Natural Sciences |
| Organization | Lafayette College |
| Date Issued | 1975 |
| Date Available | 2023-06-26 |
| Type | Article |
| Language | English |
| Bibliographic Citation | Majumdar, S. K., et al. (1975) "Teratologic Evaluation of Hexachlorophene in Mice." Proceedings of the Pennsylvania Academy of Science 49 (2): 110-112. |
| Standard Identifier | Handle 10385/dr26xz703 |
| Permalink | http://hdl.handle.net/10385/dr26xz703 |
| Rights Statement |
In Copyright
|
| Rights Holders | Penn State University Press |
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| File | Majumdar-ProceedingsofthePennsylvaniaAcademyofScience-vol49-1975.pdf | Uploaded 2023-06-26 | Public | Download |
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