Valued living and its relationship to medication adherence in patients with bipolar and comorbid substance use disorders

Bipolar disorder with comorbid substance abuse is associated with high rates of treatment nonadherence. Adherence interventions developed to date have had mixed effects in this population. Valued living (i.e., the consistency between a patient's personal values and daily actions) represents a potentially useful treatment target that may improve adherence. We investigated the relationship between valued living, medication adherence, symptoms, and functioning in a sample of 39 patients diagnosed with bipolar disorder and a comorbid substance use disorder. Results showed that greater values-action consistency explained a unique amount of variance (R-2 change = 15.2%) in medication adherence even after controlling for symptom severity, functional impairment, and other reported reasons for nonadherence. Drug use and treatment beliefs also predicted nonadherence. Findings suggest that valued living should be investigated further as a potentially malleable treatment target in future adherence intervention research.

Title	Valued living and its relationship to medication adherence in patients with bipolar and comorbid substance use disorders
Creator	Weinstock, L. M.
	Miller, I. W.
	Wenze, Susan J.
	Gaudiano, B. A.
	Tezanos, K. M.
Publisher	Journal of Nervous and Mental Disease
Academic Department	Psychology
Division	Natural Sciences
Organization	Lafayette College
Date Issued	2017
Date Available	2019-01-04T18:37:10Z
Type	Article
Language	English
Keyword	drug abuse
	Bipolar disorders
	values
	adherence
	alcohol abuse
Bibliographic Citation	Gaudiano, B. A., et al. (2017) "Valued living and its relationship to medication adherence in patients with bipolar and comorbid substance use disorders." Journal of Nervous and Mental Disease 205 (3): 178-181.
Standard Identifier	Handle 10385/2536
Standard Identifier	DOI 10.1097/NMD.0000000000000533
Permalink	http://hdl.handle.net/10385/2536
Rights Statement	In Copyright
Rights Holders	Wolters Kluwer Health, Inc.